09.00 - 10.00 - KEYNOTE LECTURE: From development to therapeutic mRNAs:

Combining genomics and expansion microscopy to understand the basic mechanisms of transcription and translation. Antonio Giraldez - Yale School of Medicine

Chair: Vincenzo Cavalieri (UniPA)

EMERGING TECHNOLOGIES

Chairs: Simona Casarosa (UniTN) and Alessandro Cellerino (SNS)

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10.00 - 10.15 - Fast, efficient and flexible manipulation of neuronal activity with single cell precision. Filippo Del Bene (INSERM)

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10.15 - 10.30 - High density electrophysiological recordings in zebrafish larvae across multiple brain regions. Marta D'Amora (IIT) 

10.30 - 11.00 - Coffee break

DISCOVERY, TOXICOLOGY AND STRESS

Chairs: Michela Ori (UniPI) and Tiziano Verri (UniSALENTO)

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11.00 - 11.15 - High throughput in vivo screening of compounds to find novel factors affecting the zebrafish habenular circuit development and linking it to neuropsychiatric disorders. Judith Habicher (UniTN)

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11.15 - 11.30 - Exploring the protective effects of secretome from Wharton's jelly mesenchymal stem cells in zebrafish. Vincenzo Cavalieri (UniPA)

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11.30 - 11.45 - Insights on the role of lysosomal protein cln5 in neurodegeneration using zebrafish as a tool. Maria Marchese (ISM)

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11.45 - 12.00 - Characterization of a zebrafish model for SPG4 Hereditary Spastic Paraplegia and in vivo drug screening. Francesca Greco (UniVR)

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12.00 - 12.15 - Dietary Probiotic reduces BPA waterborne toxicity: zebrafish as valuable model for translational research. Francesca Maradonna (UnivPM)

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12.15 - 12.30 - Evaluation of stress response in adult zebrafish (Danio rerio)

exposed to intermittent fasting. Elisa Fonsatti (UniPD)

12.30 -12.45 - Group Photo

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12.45 -14.00 - Lunch

DISEASES MODELS 1

Chairs: Dario Finazzi (UNIBS) and Natascia Tiso (UniPD)

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14.00 - 14.15 - ADA2 regulates inflammation and hematopoietic stem cells emergence via the A2bR pathway in zebrafish. Alessia Brix (UniMI)

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14.15 - 14.30 - Increased levels of beta-glucosyl-sitosterol trigger intestinal dysfunction: gut-brain axis could pave the way for neurodegeneration. Francesca Terrin (UniPD)

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14.30 - 14.45 - Hdac1 regulates cardiomyocyte proliferation during development and heart regeneration. Anja Buhler (UniULM)

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14.45 - 15.00 - Modeling Sarcoglycanopathy in Zebrafish: generation of valuable tools for enhanced disease understanding and drug screening. Francesco Dalla Barba (UniPD)

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15.00 - 15.15 - Uncovering early signs preceding disease-onset in a zebrafish model of rare tubulinopathy exhibiting untreatable neurodegeneration. Antonella Lauri (OPBG)

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15.15 - 15.45 - Coffee Break 

DISEASES MODELS II

Chairs: Livia D'Angelo (UniNA) and Daniele Tibullo (UniCT)

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15.45 - 16.00 - Zebrafish for modeling Alexander disease. Deianira Bellitto (UniGE)

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16.00 - 16.15 - The role of PS727 Stat3 regulation of Vitamin D pathway in the pathogenesis of Job's syndrome. Annachiara Tesoriere (UniPD)

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16.15 - 16.30 - Modeling rare neurodevelopmental disorders: Pitt Hopkins syndrome and de novo pathogenetic variants of TCF4 gene. Michela Ori (UniPI)

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16.30 - 16.45 - Assessment of Teen sensor fish to detect early RASopathy-associated ERK activation and its pharmacological modulation. Giulia Fasano (OPGB)

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16.45 - 17.00 - A novel model for Krabbe disease in zebrafish. Luca Mignani (UniBS)

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17.00 - 17.15 - Sponsor Talk: Tritone XS, big advantages in a small solution!. Tommaso Sala  (Tecniplast)

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17.15 - 17.30 - Poster Preview 2 

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17.30 - 18.45 - Poster Session

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19.00  - Guided tour in historical city center

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21.00  -  Social dinner